DNA vaccines are normally hard to deliver into cells. But, National Health Research Institutes researchers of Taiwan coupled electroporation while delivering DNA vaccination.
According to research, mice and hamsters immunised with new DNA vaccine developed long-lasting antibodies against SARS-CoV-2 spike protein. Antibodies peaked at eight weeks after immunisation but levels were relatively high at week 20.
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| COVID-19, New DNA vaccine effective in mice, hamsters |
Know About DNA Vaccine?
DNA vaccine is thermally stable and no cold chain-needed. DNA vaccine can induce high levels of long-lasting neutralising antibody against SARS-CoV-2. DNA vaccine can be produced quickly at lower cost. Several clinical trials have indicated the efficacy of DNA vaccines in treating infections like Ebola and influenza viruses, Zika, HIV-1.
Know About mRNA-based vaccines?
Recently Available Covid-19 vaccines is based on mRNA strands. Such vaccines increase human immune system to recognize SARS-CoV-2 virus.
Similarity between both vaccines
All Type mRNA-based and DNA based vaccines use genetic material encoding part of virus to draw out an immune response.
